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KMID : 0361020230660120857
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Korean Journal of Otolaryngology - Head and Neck Surgery
2023 Volume.66 No. 12 p.857 ~ p.864
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Long-Term Treatment Outcomes of Hypopharyngeal Cancer Using Different Surgical Modalities
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Kim Ja-Yoon
Park Young-Min
Lim Jae-Yol
Koh Yoon-Woo
Kim Se-Heon
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Abstract
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Background and Objectives In the present study, we evaluated the treatment results of hy-popharyngeal squamous cell carcinoma (HPSCC) patients and analyzed the occurrence ofsecondary primary malignancies. Treatments were based on two different surgical modalities(conventional pharyngo-laryngectomy vs. transoral surgery). In addition, prognostic factors ofthe patients were evaluated.
Subjects and Method We analyzed medical data of 232 patients diagnosed with HPSCCand underwent surgery at our hospital from January 2006 to December 2019.
Results The 5-year recurrence-free survival was 67.2% for the stage I-II group and 64.9%for the stage III-IV group. The 5-year disease-specific survival was 78.2% for the stage I-IIgroup and 54.5% for the stage III-IV group. N classification was significantly correlated withdisease relapse and patient mortality. Patient age, sex, perineural invasion, extranodal exten-sion, initial tumor stage, and early recurrence (within 6 months) were significantly associatedwith successful salvage treatment. The two surgical modalities did not yield different onco-logical outcomes. Secondary primary malignancies occurred most frequently in theesophagus, with no observed inferior survival rate in patients with second malignancies.
Conclusion The 5-year survival rate for HPSCC patients who received surgical treatmentwas 78% for stage I-II and 54% for stage III-IV. While no difference in oncological outcomewas observed based on surgical modality, the transoral surgery group showed better functional outcomes.
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KEYWORD
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Hypopharyngeal cancer, Propensity scores, Robot-assisted surgery, Second primary cancer, Surgical procedure
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